Monday, June 28, 2010

Stem Cell Research - introduction

Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.
Scientists primarily work with three kinds of stem cells from human and animals: (1) embryonic stem cells (ESCs), (2) non-embryonic "somatic" or "adult" stem cells and (3) induced pluripotent stem cells (iPSCs).
Research on stem cells continues to advance knowledge about how an organism develops from a single cell and how healthy cells replace damaged cells in adult organisms. Stem cell research is one of the most fascinating areas of contemporary biology, but, as with many expanding fields of scientific inquiry, research on stem cells raises scientific questions as rapidly as it generates new discoveries.

Cells used for reprogram

  1. Human dermal fibroblasts-fetal (cat. # 2300)
  2. Human dermal fibroblasts-neonate (cat. # 2310)
  3. Human dermal keratinocytes (cat. # 2100)

Cells support ESCs and iPSCs growth in culture
(feeder layer)

  1. Mouse embryonic fibroblasts (cat. # M7540, M7550)
  2. Mouse embryonic fibroblasts-mitomycin treated (cat. # M7550)

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